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目的探讨C-反应蛋白、临床肺部感染评分在社区获得性肺炎中的临床价值。方法将72例社区获得性肺炎患者根据抗生素使用前的痰涂片及痰培养结果分为细菌感染组(痰涂片及痰培养阳性,34例)和非细菌感染组(痰涂片及痰培养阴性,38例)。对2组治疗前及细菌感染组治疗后第3、7天检测血浆C-反应蛋白的水平,并进行临床肺部感染评分。结果细菌感染组治疗前血浆C-反应蛋白水平、临床肺部感染评分均明显高于非细菌感染组(均P<0.05)。细菌感染组治疗后第3、7天血浆C-反应蛋白水平及临床肺部感染评分均较治疗前明显降低(均P<0.05),治疗后第7天较治疗前降低更明显(均P<0.05)。结论 C-反应蛋白、临床肺部感染评分对评价社区获得性肺炎患者的病情和预后具有重要的临床指导意义。
Objective To investigate the clinical value of C-reactive protein and clinical pulmonary infection score in community-acquired pneumonia. Methods Seventy-two patients with community-acquired pneumonia were divided into bacterial infection group (sputum smear and sputum culture positive, 34 cases) and non-bacterial infection group (sputum smear and sputum culture according to sputum smear and sputum culture results before antibiotic use) Negative, 38 cases). The levels of plasma C-reactive protein in the two groups before treatment and the bacterial infection group were detected on the 3rd and 7th day after treatment, and the clinical lung infection score was also obtained. Results Before treatment, the plasma C-reactive protein level and clinical lung infection score in bacterial infection group were significantly higher than those in non-bacterial infection group (all P <0.05). The levels of plasma C-reactive protein and clinical lung infection in the bacterial infection group were significantly lower than those before treatment on the 3rd and 7th day (all P <0.05), and decreased significantly on the 7th day after treatment (P < 0.05). Conclusion C-reactive protein and clinical lung infection score have important clinical significance for evaluating the condition and prognosis of patients with community-acquired pneumonia.