The Anjiayingzi gold deposit in Chifeng County, Inner Mongolia is located in the central part of the gold mineralization belt of the northern margin of the North China Craton (NCC), and is adjacent to the Paleozoic Inner Mongolia-Da Hinggan Mountains orogenic belt in the north. The Chifeng-Kaiyuan fault, which separates the NCC from this orogenic belt, is considered to be a regional ore-controlling structure. The Anjiayingzi gold deposit is a mediate-size quartz lode-gold deposit and is hosted by the Anjiayingzi quartz monzonite that was emplaced into the basement composed of early Precambrian gneisses. Rhyolitic and porphyritic dikes are generally associated with the gold mineralization. Zircon U-Pb analyses suggest that the Anjia- yingzi granite was emplaced from 132 Ma to 138 Ma, while the rhyolitic dikes that occupy the same fracture system as the gold-bearing quartz veins and locally crosscut the gold lodes crystallized from 125 Ma to 127 Ma. These results constrain the mineralization age between 126 Ma and 132 Ma, early Cretaceous time for the Anjiayingzi gold deposit. This mineralization age is consistent with that of the gold deposits in other major gold-bearing areas of the NCC, such as the Jiaodong Peninsula and the Xiaoqinling Mountain, and specially is roughly coeval with the geodynamic reversion of the NCC in Mesozoic. This coincidence probably indicates that the gold deposits in the NCC, including the Anjiayingzi deposit, formed in a similar geodynamic setting characterized by large-scale thinning of the lithosphere underlying the NCC.