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目的探究胸腔镜下肺癌根治术治疗早期非小细胞肺癌(NSCLC)患者对临床效果、并发症及预后的影响。方法选取2015年4月~2016年4月内蒙古医科大学附属医院胸外科收治的116例早期NSCLC患者临床资料进行分析,将其依据不同术式分成对照组(58例)与研究组(58例)。对照组行常规开胸肺癌根治术,研究组行胸腔镜下肺癌根治术,比较两组临床指标、并发症发生率以及生活质量评分情况。结果两组淋巴结清扫量差异无统计学意义(P>0.05)。研究组术中出血量、引流管置放时间、术后24 h VAS评分、住院时间均优于对照组,差异有高度统计学意义(P<0.01);研究组并发症总发生率显著低于对照组,差异有高度统计学意义(P<0.01);研究组生活质量评分中,功能状况、情感状况、身体状况、社会/家庭状况均高于对照组,差异有高度统计学意义(P<0.01)。结论胸腔镜下肺癌根治术能提高早期NSCLC疗效,且术后并发症少,安全性高,预后佳,具有临床推广及应用价值。
Objective To investigate the clinical effects, complications and prognosis of patients undergoing thoracoscopic radical resection of lung cancer for early stage non-small cell lung cancer (NSCLC). Methods The clinical data of 116 patients with early stage NSCLC who were admitted to Department of Thoracic Surgery, Affiliated Hospital of Inner Mongolia Medical University from April 2015 to April 2016 were analyzed and divided into control group (58 cases) and study group (58 cases) . The control group underwent conventional thoracotomy for radical resection of lung cancer. The study group underwent thoracoscopic radical resection of lung cancer. The clinical indexes, complication rates and quality of life scores were compared between the two groups. Results There was no significant difference in lymph node dissection between the two groups (P> 0.05). The bleeding volume of the study group, drainage tube placement time, VAS score and hospital stay at 24 h postoperatively were all significantly higher than those in the control group (P <0.01). The overall complication rate in the study group was significantly lower than that in the control group There was a significant difference between the two groups in the control group (P <0.01). In the study group, the functional status, emotional status, physical status and social / family status were higher than those in the control group, the difference was highly statistically significant (P < 0.01). Conclusions Thoracoscopic radical resection of lung cancer can improve the curative effect of early stage NSCLC, and it has few postoperative complications, high safety and good prognosis. It has clinical application and promotion value.