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目的:本文旨在探讨表皮生长因子受体EGFR与慢性外阴营养不良的关系及HIFV治疗对其表达的影响。方法:取慢性外阴营养不良患者病损较重区皮肤HIFV治疗前后局部活检,经免疫组化方法,检测表皮生长因子受体EGFR在HIFV治疗前后病变皮肤组织中的表达情况,对比其在HIFV治疗前后病变皮肤组织中表达的差异。结果:慢性外阴营养不良者HIFV治疗后阳性表达率降低(P<0.05),结论:H1FV为慢性外阴营养不良患者提供了安全高效的治疗,值得临床推广应用。
Objective: This article aims to investigate the relationship between epidermal growth factor receptor EGFR and chronic vulvar dystrophy and the effect of HIFV therapy on its expression. Methods: Local biopsy was performed before and after treatment of HIFV in patients with chronic genital malnutrition. Immunohistochemistry was used to detect the expression of epidermal growth factor receptor EGFR in the skin tissues before and after HIFV treatment. Compared with HIFV treatment Differences in the expression of skin lesions before and after lesions. Results: The positive expression rate of HIFV patients with chronic vulvar dystrophy decreased (P <0.05). Conclusion: H1FV provides safe and effective treatment for patients with chronic vulvar dystrophy and is worthy of clinical application.