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目的:探讨内障丸对抗子宫内膜抗体阳性大鼠抗子宫内膜抗体水平的影响。方法:将Wistar雌性成年大鼠随机分为6组,中药低剂量组(内障丸)、中药高剂量组(内障丸)、中药对照组(六味地黄丸)、西药对照组(醋酸泼尼松片)、模型组、空白组;从第1次免疫后第9周开始给药,连续3周,三周后检测内障丸对抗子宫内膜抗体水平的影响。结果:内障丸可明显降低抗子宫内膜抗体水平,提高大鼠的窝产仔鼠数。结论:内障丸能改善子宫内环境,抑制流产的发生。
Objective: To investigate the effect of pill on the anti-endometrial antibodies in endometrial antibody-positive rats. Methods: Wistar female adult rats were randomly divided into 6 groups: low dose Chinese medicine group (cataract pill), high dose Chinese medicine group (cataract pill), Chinese medicine control group (Liuweidihuangwan), western medicine control group Pineal), model group and blank group. The administration was started at the 9th week after the first immunization, and the effect of the pill on the endometrial antibody level was tested three weeks and three weeks later. Results: The pill can significantly reduce the level of anti-endometrial antibody and increase the number of litter in rats. Conclusion: The pill can improve the uterine environment and inhibit the occurrence of miscarriage.