论文部分内容阅读
目的观察赛庚啶对大鼠脑血流量、心肌血流量及肾血流量的影响及其对以ADP、凝血酶、肾上腺素复合物为诱导剂的实验性脑血栓的影响。方法：放射性微球法。结果：赛庚啶iv2mg·kg(－1)可以使正常SD大鼠脑血流量增加28．6％，心肌血流量增加43．0％，肾皮质血流量增加45．6％，与对照组相比差异有显著性。ivlmg·kg(－1)可以抑制实验性脑血栓的形成。结论：赛庚啶可以改善心、脑、肾的血液循环。
Objective To observe the effect of cyproheptadine on cerebral blood flow, myocardial blood flow and renal blood flow in rats and its effect on experimental cerebral thrombosis induced by ADP, thrombin and adrenaline complex. Methods: Radioactive microspheres method. Results: The results showed that cyproheptadine iv2mg · kg (-1) increased the cerebral blood flow of normal SD rats by 28.6%, the myocardial blood flow increased by 43.0% and the renal cortex blood flow increased by 45.6% The difference was significant. ivlmg · kg (-1) can inhibit the formation of experimental cerebral thrombosis. Conclusion: Cyproheptadine can improve the blood circulation of heart, brain and kidney.