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目的观察美托洛尔联合贝那普利治疗特发性扩张型心肌病伴心力衰竭的疗效。方法 30例特发性扩张型心肌病伴心力衰竭患者采用美托洛尔联合贝那普利治疗。检测治疗前、治疗3、6、12个月后,心功能分级、左室射血分数(LVEF)、左室舒张末期内径(LVEDD)、左心室缩短速率(FS)等指标的变化。结果治疗3、6、12个月后各项指标逐步改善,以6、12个月后为明显(P<0.05)。结论美托洛尔联合贝那普利治疗特发性扩张型心肌病伴心力衰竭可显著改善心功能,提高LVEF、FS,缩小LVEDD。
Objective To observe the efficacy of metoprolol combined with benazepril in the treatment of idiopathic dilated cardiomyopathy with heart failure. Methods Thirty patients with idiopathic dilated cardiomyopathy and heart failure were treated with metoprolol combined with benazepril. The changes of cardiac function classification, left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD) and left ventricular shortening rate (FS) were measured before treatment and 3, 6 and 12 months after treatment. Results After 3, 6, and 12 months of treatment, the indexes gradually improved, which were obvious after 6 and 12 months (P <0.05). Conclusion Metoprolol combined with benazepril treatment of idiopathic dilated cardiomyopathy with heart failure can significantly improve cardiac function, increase LVEF, FS, reduce LVEDD.