风湿性心脏病患儿,常常每月注射长效青霉素以预防链球菌感染,防止风湿热复发。最近,我们在心脏专科门诊中见到3例患儿,用药后引起过敏性休克,为了吸取教训,现报告如下,以供参考。例1 男,11岁,住院号216511;诊断为风湿性心脏病二尖瓣关闭不全。过去无药物过敏史。每月肌注长效青霉素120万单位,共20余次,中间曾有2次注射后感觉头晕,认为是饥饿所致,未加重视。最后一次注射,先皮试,结果阴性后给予肌注长效青霉素120万单位,注射后即感头晕、胸闷、腹痛、呼吸困 Children with rheumatic heart disease, often monthly injection of long-acting penicillin to prevent streptococcal infection, to prevent the recurrence of rheumatic fever. Recently, we have seen three patients in cardiac specialist clinics that cause anaphylactic shock after medication. To draw lessons, we report the following for reference. Case 1 male, 11 years old, hospital number 216511; diagnosis of rheumatic heart disease mitral regurgitation. Past history of drug allergy. Long-term intramuscular injection of penicillin 1.2 million units a total of more than 20 times, there have been 2 times after the injection of feeling dizzy, that is caused by hunger, did not pay attention. The last injection, the first skin test, the results were negative after giving intramuscular injection of penicillin 120 million units, that is, dizziness, chest tightness, abdominal pain, breathing difficulties