炎症和感染往往导致机体生长功能的下降，由此推测，机体免疫系统对下丘脑－垂体－性腺轴（HPG）具有一定的影响。同时从Besodovsky首先提出“免疫－神经－内分泌调节网络学说”，指出神经内分泌系统与免疫系统之间存在着完整的功能性调节环路，而后者主要是通过神经肽、激素和 Inflammation and infection often lead to the decline of the growth function of the body, suggesting that the immune system of the body has a certain influence on the hypothalamic-pituitary-gonadal axis (HPG). At the same time, from Besodovsky first proposed “immune - neuroendocrine regulation network theory”, pointed out that there is a complete functional regulatory loop between the neuroendocrine system and the immune system, which is mainly through neuropeptides, hormones and