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选用健康公恒河猴６只每组２只，以Ｂｒ．ｏｖｉｓ进行１、０．１、０．０１亿菌初感染后３５天，分别再以１０、５、１亿菌重复感染。各组分别在初感染１５天，再感染０．５、１、２、３、６、８、１０个月时测定血清中各种抗体。结果Ｒ－ＳＡＴ、Ｒ－ＧＤＴ、Ｒ－ＲＢＰＴ在初感染０．５个月开始转阳，再感染１个月Ｒ－２ＭＥ（１、２组）转阳；再感染０．５个月Ｒ－ＳＡＴ达峰值后下降，８个月时又达峰值且与Ｒ－２ＭＥ同步；在再感染６个月至８个月时，１、２号猴从血液中分离到类Ｂｒ．ｏｖｉｓ培养物。此结果与绵羊人工感染Ｂｒ．ｏｖｉｓ结果相似。
Selection of healthy male rhesus monkeys 6 per group of two, with Br. Ovis 1,010,010 million bacteria infected with 35 days after the initial infection, and then 105,5 million bacteria repeated infections. Each group were infected at the initial infection of 15 days, then 0.5, 1, 2, 3, 6, 8, 10 months when the determination of serum antibodies. Results R-SAT, R-GDT and R-RBPT started to turn positive at 0.5 months after initial infection, and again at 1 month after R-2ME (groups 1 and 2). R-SAT Peaked and then peaked, peaked at 8 months and synchronized with R-2ME. Broths 1,2 were isolated from blood at weeks 1 and 6 after re-infection for 6 months to 8 months. ovis culture. This result was associated with artificial infection of Br with sheep. ovis similar results.