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该文通过检测4组病人(包括3个梗阻性黄疸组:轻度黄疸、中重度黄疸、梗阻性黄疸术后并发肾衰组,和1个对照组:非黄疸手术组)的血浆心钠素含量。发现各黄疸组病人心钠素均比非黄疸组病人高;各组患者术后第1天心纳素浓度均较术前高,术后另5天除梗阻性黄疸合并肾衰组外,心钠素水平基本都下降至术前水平;梗阻性黄疸合并肾衰组患者心钠素水平持续升高,术后第5天心钠素水平最高;心钠素浓度与总胆红素、谷丙转氨酶、BUN、Cr及尿量明显相关。
In this paper, plasma atrial natriuretic peptide (atrial natriuretic peptide) was measured in four groups of patients (including three obstructive jaundice groups: mild jaundice, moderate-severe jaundice, renal failure group after obstructive jaundice and one control group: non-jaundice operation group) content. Found that all patients with jaundice atrial natriuretic peptide were higher than non-jaundice patients; each group of patients on the first day postoperative plasma concentrations were higher than preoperative, another five days after the addition of obstructive jaundice combined with renal failure group, sodium The level of atrial natriuretic peptide in patients with obstructive jaundice and renal failure group continued to increase, with the highest level of atrial natriuretic peptide on the fifth postoperative day. The levels of atrial natriuretic peptide and total bilirubin, alanine aminotransferase, BUN, Cr and urine output were significantly correlated.