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中分子物质(简称中分子)是指存在于血液中的分子量在297.6～4960.5u(300～5000 dalton)之间的混合物。国外大量研究资料已证明,中分子除参与尿毒症的发病外,还对许多疾病有致病作用;而血中巯基的含量与某些疾病的症状有着密切的关系。为探讨中分子物质及巯基含量与单纯性肥胖之间存在何种联系,我们对单纯性肥胖患者进行血中中分子及巯基含量的测定,并讨论其临床意义。
Medium molecular substances (referred to as the middle molecule) refers to the mixture exists in the blood of molecular weight between 297.6 ~ 4960.5u (300 ~ 5000 dalton). A large number of foreign research data have proved that, in addition to participating in the pathogenesis of uremia, but also for many diseases have pathogenic role; and blood levels of sulfhydryl and some diseases have a close relationship. In order to explore the relationship between molecular weight and sulfhydryl content and simple obesity, we measured the levels of intramolecular and sulfhydryl in the patients with simple obesity and discussed its clinical significance.