近年研究表明:无论在体内或体外系统,携带EB病毒基因的细胞都存在着EB病毒核抗原(EBNA);核酸杂交试验又证实EB病毒DNA的检出,与EBNA的表达有密切关系。本文应用抗补体免疫荧光方法,检测鼻咽增生性病变患者血清中的EBNA抗体,通过此抗体滴度的变化,探讨鼻咽增生性病变与EB病毒感染、基因嵌入和抗体形成之间的联系,从而说明它在癌变上的意义。 In recent years, studies have shown that: Epstein-Barr virus nuclear antigen (EBNA) is present in cells carrying the EB virus gene in both in vivo and in vitro systems; nucleic acid hybridization assays confirm the detection of Epstein-Barr virus DNA, which is closely related to the expression of EBNA. In this paper, anti-complementary immunofluorescence was used to detect EBNA antibodies in serum of patients with nasopharyngeal proliferative diseases. Through the change of this antibody titer, the relationship between nasopharyngeal proliferative lesions and EB virus infection, gene insertion and antibody formation was explored. This shows its significance in cancer.