经鼻投与黄体生成激素释放激素类似物(LHRHa)作为治疗子宫内膜异位症的药物在日本临床已经应用,这种制剂也能作为避孕药使用而受到瞩目。尽管在医学飞速发展的今天也未能完全自由控制妊娠。五十年代出现了口服避孕药和宫内节育器比古典的避孕药效果良好。但目前仍在不懈努力减轻长期使用这些药物引起的副作用。特别是口服避孕药比初期应用者含类固醇量减少了许多,但对心血管的影响作为主要的副作用仍有争论。就此而 Nasal administration of luteinizing hormone releasing hormone analogue (LHRHa) has been used clinically as a medicament for the treatment of endometriosis, and this preparation is also attracting attention as a contraceptive. Although the rapid development of medicine today also not completely free to control pregnancy. The fifties appeared oral contraceptives and IUD better than classical contraceptives. However, efforts are still being made to alleviate the side effects caused by long-term use of these drugs. In particular, oral contraceptives than the initial application of steroid-containing much lower, but the cardiovascular effects as the main side effects still controversial. That’s it