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目的:探讨应用磁共振弥散/灌注成像技术判断急性脑梗死后缺血半暗带IP存在的范围和时间规律。方法:对72例发病时间在1～24h的急性脑梗死患者行常规MRI、磁共振弥散加权成像(DWI)和磁共振灌注加权成像(PWI)确定IP的范围,计算梗死中心区、IP区及对侧镜像区的ADC值和rADC值并加以比较。结果:26例发病时间<6h的患者PWI显示存在低灌注区者,其中PWI>DWI者21例,30例发病时间在6～24h的患者PWI显示存在低灌注区者,其中PWI>DWI者2例;PWI>DWI者病灶中心ADC值与IP区及对侧镜像区ADC值差异有统计学意义,其IP区ADC值与其对侧镜像区差异无统计学意义。结论:DWI和PWI结合能灵敏的判断IP的存在,IP存在的时间窗有一定的个体差异。
Objective: To investigate the extent and time of magnetic resonance diffusion / perfusion imaging in detecting the presence of IP in ischemic penumbra after acute cerebral infarction. Methods: Seventy-two patients with acute cerebral infarction with onset time of 1 ~ 24h were examined by conventional MRI, DWI and PWI to determine the IP range. The infarct center area, IP area and The contralateral mirror area ADC values and rADC values and compared. Results: The PWI of 26 patients with onset time <6h showed low perfusion area, including 21 patients with PWI> DWI and 30 patients with low perfusion in PWI> 6h. PWI> DWI 2 For example, the ADC value of lesion center in PWI> DWI was significantly different from that in IP area and contralateral mirror area, and the ADC value of IP area was not significantly different from that of contralateral mirror area. Conclusion: The combination of DWI and PWI can sensitively judge the existence of IP, and there are some individual differences in the time window of IP.