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目的评价万古霉素在儿科患者中的使用情况及特点,促进临床合理用药。方法通过回顾性分析静脉用万古霉素的住院患儿,提取患儿的病原学检查、疾病情况、药物治疗监测情况、用药时间、疗效等数据进行统计分析。结果 2013年,94例次患儿病例中,经验治疗比例为65.96%;有效率为78.72%;用药原因中肺部感染所占比例最高34.86%;微生物及药敏送检率为96.81%,阳性结果中葡萄球菌占20.81%(36/173);治疗药物监测比例为17.02%。结论临床用万古霉素以经验用药为多,使用基本合理,但用药及监测细节上仍存在一些问题。
Objective To evaluate the use and characteristics of vancomycin in pediatric patients and promote the rational use of clinical medicine. Methods By retrospective analysis of intravenous vancomycin hospitalized children, extraction of children with etiological examination, disease conditions, drug treatment monitoring, medication time, efficacy and other data for statistical analysis. Results In 2013, 94.96% of the children had experience in treatment. The effective rate was 78.72%. The proportion of pulmonary infection in medication was the highest, 34.86%. The rate of microbiological and drug susceptibility testing was 96.81%. The positive rate Staphylococcus aureus accounted for 20.81% (36/173), and the therapeutic drug monitoring rate was 17.02%. Conclusion The clinical use of vancomycin is more than the experience of medication, the use of basic reasonable, but there are still some problems on medication and monitoring details.