肢端肥大症病人可患有心血管、代谢及风湿等合并症,癌症的发病率也较高。作者就肢端肥大症合并症的可逆性作一综述。 心血管合并症 肢端肥大症可有各种心血管合并症,病人(尤其男性)的死亡率因此而增加。有关治疗对这些合并症转归的影响资料目前尚少。 一、高血压 30％的肢端肥大症病人有高血压。一些报告提示其高血压与年龄、病程及GH水平相关。病人的可交换钠、总体钠和水、血浆容量及细胞外液量增加,血浆 Acromegaly patients may have cardiovascular complications such as metabolism and rheumatism, the incidence of cancer is also higher. The authors reviewed the reversibility of acromegalic complications. Cardiovascular complications Acromegaly may have a variety of cardiovascular comorbidities, the patient (especially men) mortality increased accordingly. The impact of treatment on the outcome of these complications is still low. First, hypertension 30% of acromegaly patients have high blood pressure. Some reports suggest that their hypertension, age, duration and GH levels. Patient’s exchangeable sodium, total sodium and water, plasma volume and extracellular fluid volume increased, plasma