冠状动脉疾病(CAD)和其最重要并发症———急性心肌梗塞(MI)是目前发达国家导致丧失劳动能力和死亡的主要原因。尽管CAD/MI的相关遗传基础还知之甚少,但其多发风险因素已确定,包括家族史、高血压、高胆固醇血症、肥胖、吸烟和糖尿病。虽然特异基因还未确定,但对患病同胞对进行 Coronary artery disease (CAD) and its most important complication, acute myocardial infarction (MI), are the major causes of incapacity and death in developed countries. Although little is known about the underlying genetic basis of CAD / MI, multiple risk factors have been identified, including family history, hypertension, hypercholesterolemia, obesity, smoking and diabetes. Although specific genes have not been identified, they are performed on diseased sib pairs