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目的:优选金牛咽炎胶囊的提取工艺。方法:以浸膏率、绿原酸转移率为综合指标,采用L9(34)正交试验,以乙醇体积分数、加醇量、提取时间、提取次数为考察因素。对提取工艺条件进行优选。结果:最佳提取工艺条件为70%乙醇8倍量,回流提取3次,每次1 h。结论:优选的提取工艺条件稳定可行。
Objective: To optimize the extraction process of Jinniu pharyngitis capsules. Methods: The extraction rate and chlorogenic acid transfer rate were used as the comprehensive indexes. The L9 (34) orthogonal test was used to investigate the effects of ethanol volume fraction, alcohol amount, extraction time and extraction times. Optimization of the extraction process conditions. Results: The optimal extraction conditions were 8 times of 70% ethanol and refluxed for 3 times for 1 hour. Conclusion: The optimal extraction process conditions are stable and feasible.