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目的探讨胰岛素瘤的临床特点及诊治方法。方法回顾性分析8例胰岛素瘤患者的临床资料。结果7例患者临床表现均符合W h ipp le三联症。平均病程23个月,B超和CT联合诊断为6例,单发瘤5例,多发瘤3例。7例行手术切除,1例术中未能找到。术后随访中,1例为MEN-I,2例出现恶变并转移。结论外科手术是治疗胰岛素瘤的主要方法,手术方式应根据病变的性质、部位、数量等因素确定,术后随访非常必要。
Objective To investigate the clinical features, diagnosis and treatment of insulinoma. Methods The clinical data of 8 patients with insulinoma were retrospectively analyzed. Results The clinical manifestations of all 7 patients were consistent with W h ipp le triad. The average duration of the disease was 23 months. B-ultrasonography and CT were combined to diagnose 6 cases. There were 5 cases of single tumors and 3 cases of multiple tumors. Surgical resection was performed in 7 cases and 1 case was not found during the operation. During follow-up, one patient had MEN-I, and 2 patients had malignant transformation and metastasis. Conclusions Surgery is the main method for the treatment of insulinoma. Surgical methods should be based on the nature, location and quantity of the lesions. Follow-up after surgery is very necessary.