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目的探讨高血压患者左室重量指数、血尿酸与颈动脉内一中膜厚度的相关性。方法分别对100例高血压患者和40例正常对照组进行超声检查分别测量室间隔厚度(IVST)、左室后壁厚度(LVPWT)、左室舒张末期容积(LVDd)、颈动脉内一中膜厚度(IMT)、斑块大小及血流动力学等指标,计算左室重量指数(LVMI)以及血尿酸水平测定。结果①与正常对照组相比,高血压患者IMT明显增厚,血流动力学呈低速高阻状态。②高血压左室肥厚患者,IMT与血UA水平高于左室非肥厚的高血压患者及正常对照组患者。结论高血压患者左室重量指数、血尿酸与颈动脉内一中膜厚度呈正相关。
Objective To investigate the relationship between left ventricular mass index, serum uric acid and a carotid artery intima-media thickness in hypertensive patients. Methods 100 cases of hypertensive patients and 40 cases of normal control group were examined by ultrasound to measure the interventricular septum thickness (IVST), left ventricular posterior wall thickness (LVPWT), left ventricular end-diastolic volume (LVDd), a carotid artery Thickness (IMT), plaque size and hemodynamics and other indicators, calculate the left ventricular mass index (LVMI) and serum uric acid levels were measured. Results ① Compared with the normal control group, the IMT of hypertensive patients was significantly thicker and the hemodynamics showed a state of low speed and high resistance. ② In hypertensive patients with left ventricular hypertrophy, IMT and blood UA levels were higher than those in non-hypertensive patients with left ventricular hypertrophy and normal controls. Conclusion There is a positive correlation between left ventricular mass index, serum uric acid and a carotid intima-media thickness in hypertensive patients.