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现代结核病学的迫切任务之一是提高结核病诊断的质量及结核病人治疗的效果。包括异烟肼及利福平的近代化疗使绝大多数新发现破坏性肺结核病人迅速终止排菌及空洞愈合。大多数病例,先停止排菌然后空洞愈合,而停止排菌持久与否是化疗效果的重要预后指标之一。为了评价停止排菌的持久性,人们采用综合检查方法,其中也包括动物试验。为了研究排菌进程以及动物试验在发现近代化疗早期阶段“隐匿性”排菌的作用,作者进行了如下工作。91例新发现破坏性肺结核病人,男82例,女9例,年龄18~72岁。其中局灶型5例,浸润型71例,播散型肺结核11例,纤维空洞型3
One of the urgent tasks of modern TB medicine is to improve the quality of TB diagnosis and TB treatment. Modern chemotherapy, including isoniazid and rifampicin, has resulted in the rapid termination of mycobacterial discharge and empty healing in the vast majority of newly found destructive pulmonary tuberculosis patients. In most cases, the first step is to stop the row of bacteria and empty cavity healing, and to stop row bacteria lasting or not is one of the important prognostic indicators of the effect of chemotherapy. In order to evaluate the persistence of stopping mycobacteria, a comprehensive test is used, including animal tests. In order to study the process of bacteria discharge and the role of animal experiments in detecting “occult” mycobacteria in the early stages of modern chemotherapy, the authors carried out the following work. 91 cases of newly discovered destructive pulmonary tuberculosis patients, 82 males and 9 females, aged 18 to 72 years. There were 5 focal lesions, 71 infiltrative lesions, 11 disseminated pulmonary tuberculosis and 3 fibrous cavities