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目的:探讨一种安全、有效、费用低、不良反应相对较少的终止早孕的镇痛方法。方法:自愿参加该项工作,无相关禁忌证且孕周<8周的要求行人工流产的早孕妇女101例,随机分为三组,对三组的镇痛效果、宫颈松弛情况及人工流产综合征(RAAS)发生率进行比较。结果:镇痛效果Ⅰ组效果最佳,与Ⅱ、Ⅲ组比较差异有统计学意义(P<0.001)。Ⅱ组效果次之,与Ⅲ组比较差异有统计学意义(P<0.001)。宫颈松弛情况Ⅰ组效果最佳,Ⅱ组次之,Ⅰ组与Ⅱ、Ⅲ组比较均P<0.001;Ⅱ、Ⅲ组比较,P<0.001;三者之间差异有统计学意义。RAAS发生率Ⅰ组发生率最低,Ⅱ组其次,Ⅰ、Ⅱ组比较差异有统计学意义(P<0.05);Ⅰ、Ⅲ组比较差异有统计学意义(P<0.01);Ⅱ、Ⅲ组比较差异亦有统计学意义(P<0.05)。结论:碳酸利多卡因伍用盐酸山莨菪碱具有安全有效、操作简便、价格低廉的特点,在基层医院是一种较好的能够广泛应用的镇痛方法。
Objective: To explore a safe, effective, low cost, less adverse reactions to terminate early pregnancy analgesia. Methods: 101 volunteers who volunteered to participate in the work and who had no contraindications and were less than 8 weeks pregnant gestational age required abortion were randomly divided into three groups. The analgesic effect, cervical relaxation and abortion of the three groups Sign (RAAS) incidence rates were compared. Results: The analgesic effect was the best in group Ⅰ, and there was significant difference between group Ⅱ and Ⅲ (P <0.001). The second group was the second, with the difference between the three groups was statistically significant (P <0.001). Cervical relaxation in group Ⅰ was the best, followed by group Ⅱ, group Ⅰ and Ⅱ, Ⅲ were more than P <0.001; Ⅱ, Ⅲ group, P <0.001; between the three was statistically significant. The incidence of RAAS was the lowest in group Ⅰ, while in group Ⅱ, there was a significant difference between groups Ⅰ and Ⅱ (P <0.05); there was a significant difference between groups Ⅰ and Ⅲ (P <0.01) The difference was also statistically significant (P <0.05). Conclusion: Lidocaine carbonate is safe and effective with anisodamine hydrochloride. It is simple and easy to operate and has low price. It is a good analgesic method that can be widely used in primary hospitals.