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目的:分析和比较医院实施“阳光用药”信息直报系统前后对临床合理用药的成效。方法:抽取2016年1月—2016年12月间实施“阳光用药”信息直报系统后的30 755张处方(研究组),另抽取2015年1月—2015年12月间未实施“阳光用药”信息直报系统前的19 964张处方(对照组),比较实施前后两组处方用药的不合理率,基本用药的使用率、抗菌药物的使用率(包括住院抗菌药物的使用率、门诊抗菌药物的使用率、急诊抗菌药物的使用率)以及住院患者抗菌药物使用强度。结果:实施“阳光用药”信息直报系统后,处方用药的合理率为99.00%明显高于实施前为94.50%(χ~2=6.514,P<0.05);实施“阳光用药”信息直报系统后住院患者抗菌药物的使用率、门诊抗菌药物的使用率、急诊抗菌药物使用率以及住院患者抗菌药物使用强度分别为52.10%、15.47%、33.82%和46.86%,而实施前分别为51.22%、15.76%、34.02%和46.18%,两组均符合“阳光用药”的指标要求,但经组间比较其差异无统计学意义(P>0.05)。结论:实施“阳光用药”信息直报系统能够有效提升处方用药的合理性,对于促进医药药学的健康持续发展和临床合理用药等具有重要的意义。
OBJECTIVE: To analyze and compare the clinical effectiveness of clinical medication before and after the implementation of “sunshine medication ” information direct reporting system in hospitals. Methods: A total of 30 755 prescriptions (study group) from January 2016 to December 2016 after the implementation of the “Sun-use information” direct-reporting system were collected and the data were extracted from January 2015 to December 2015 without implementation of 19 1964 prescriptions (control group) before sunshine information system were compared with those of the two groups before and after the implementation of prescription drugs, the rate of use of basic drugs and the usage of antibiotics (including the use of hospital antibacterials Rate, the use of outpatient antibacterials, and the use of emergency antibacterials) and the intensity of antibacterial use in hospitalized patients. The results showed that the reasonable rate of prescription medication was 99.00%, which was significantly higher than 94.50% (χ ~ 2 = 6.514, P <0.05) before the implementation of “Sunshine Medicine” The use of antibacterials, inpatient antibacterials, emergency antibacterials and inpatients were 52.10%, 15.47%, 33.82% and 46.86% respectively after inpatient direct reporting system Which was 51.22%, 15.76%, 34.02% and 46.18% respectively. Both of the two groups were in accordance with the index of “sunshine medicine”, but there was no significant difference between groups (P> 0.05). Conclusion: The implementation of “sunshine medicine ” information reporting system can effectively enhance the rationality of prescription medication, which is of great significance to promote the healthy and sustainable development of pharmaceutical pharmacy and clinical rational use of drugs.