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目的:观察无创性正压通气联合醒脑静治疗急性一氧化碳中毒的疗效及安全性,寻找治疗高原地区急性一氧化碳中毒的新的有效治疗途径。方法:2010年3月─2011年3月(海拔2 700m～3 600m)收治急性CO中毒24例,除1例入院时已死亡外,余在给予无创性正压通气和常规治疗的基础上应用醒脑静治疗,根据临床疾病诊断依据治愈好转标准和对照组进行疗效比较。结果:治疗组治愈率为95.7%,对照组治愈率为73.7%,两组比较差异有显著性(P<0.01)。结论:早期无创性正压通气联合醒脑静治疗高原地区急性一氧化碳中毒,疗效优于高频吸氧组。
Objective: To observe the efficacy and safety of noninvasive positive pressure ventilation combined with xingnaojing in treating acute carbon monoxide poisoning, so as to find a new and effective therapeutic approach for the treatment of acute carbon monoxide poisoning in the plateau area. METHODS: From March 2010 to March 2011 (altitude 2700m ~ 3600m), 24 cases of acute CO poisoning were admitted. Except for one case died on admission, non-invasive positive pressure ventilation and routine treatment were used on the basis of Xingnaojing treatment, based on the diagnosis of clinical disease based on the improvement of cure and control group to compare the efficacy. Results: The cure rate of the treatment group was 95.7%, the cure rate of the control group was 73.7%, the difference between the two groups was significant (P <0.01). Conclusion: The combination of early noninvasive positive pressure ventilation and Xingnaojing in the treatment of acute carbon monoxide poisoning in the plateau is better than that in high frequency oxygen inhalation group.