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目的 探讨鞍区肿瘤并发垂体危象的发生机理、临床表现、诊断及救治。方法 通过3例鞍区肿瘤并发垂体危象的病人,了解诱发因素,观察临床表现,给予及时诊断和适当的救治。结果 该组病人经抢救治疗,危象均被解除。结论 ①鞍区肿瘤伴垂体前叶功能减退的病人因某种诱因可发生垂体危象。②治疗的关键是尽早静脉补充大量的氢化可的松,继而给予维持量。③对有垂体前叶功能低下的病人不要随意停用肾上腺皮质激素维持量,遇有应激状态应提前增加其用量,防止危象的发生。
Objective To investigate the mechanism, clinical manifestation, diagnosis and treatment of pituitary crisis in sellar region tumors. Methods Three patients with secundum tumor complicated with pituitary crisis were involved in the investigation of the predisposing factors and the clinical manifestations. The timely diagnosis and appropriate treatment were given. Results The group of patients after rescue treatment, the crisis were lifted. Conclusion ① Saddle area tumor with anterior pituitary dysfunction in patients with some incentives may occur pituitary crisis. ② The key is to treat as soon as possible intravenous hydrocortisone supplementation, and then give the maintenance dose. ③ for patients with hypopituitarism anterior pituitary dysfunction do not discontinue adrenal cortical hormone maintenance in case of stress should increase its dosage in advance to prevent the occurrence of the crisis.