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目的:探讨控制血压对中老年男性高血压患者国际前列腺增生症状评分(IPSS)和最大尿流率(Qmax)的影响。方法:收集安徽安庆农村地区50～75岁男性原发性高血压患者193例,连续4周服用长效二氢吡啶类L型钙离子通道阻滞剂氨氯地平,观察基线血压水平及血压下降水平对IPSS和Qmax的影响。结果:4周后研究人群收缩压和舒张压分别下降了(16.8±16.7)、(8.1±7.7)mmHg(P<0.01);IPSS下降了(2.5±5.5)分(P<0.01),Qmax增加了(0.2±4.7)ml/s(P=0.46)。Qmax变化水平与基线血压及血压变化水平没有显著性差异。IPSS下降水平与血压下降水平没有显著性差异,但与基线血压水平有显著性差异。结论:在中老年男性高血压人群中,控制血压有利于预防和减轻BPH的主观症状。基线血压水平越高,BPH的主观症状经过降压治疗后改善越明显。
Objective: To investigate the effects of blood pressure control on the IPSS and Qmax of middle-aged and elderly patients with essential hypertension. Methods: A total of 193 essential hypertension patients aged 50 ~ 75 in rural areas of Anqing, Anhui province were enrolled in this study. Long-acting dihydropyridine L-type calcium channel blocker amlodipine was administrated for 4 weeks continuously. The baseline blood pressure and blood pressure Impact of Level on IPSS and Qmax. Results: After 4 weeks, systolic and diastolic blood pressure decreased by (16.8 ± 16.7), (8.1 ± 7.7) mmHg (P <0.01), IPSS decreased by (2.5 ± 5.5) (0.2 ± 4.7) ml / s (P = 0.46). There was no significant difference between Qmax and baseline blood pressure and blood pressure. There was no significant difference between IPSS level and blood pressure level, but there was significant difference with baseline blood pressure level. Conclusion: In middle-aged and elderly hypertensive population, controlling blood pressure is good for preventing and reducing the subjective symptoms of BPH. The higher the baseline blood pressure level, the more subjective symptoms of BPH improved after antihypertensive treatment.