家族性转甲状腺素蛋白淀粉样变性(familial transthyretin amyloidosis)是一种具有遗传性的以转甲状腺素蛋白为沉积物的淀粉样变性类疾病,以常染色体显性遗传为其特征,并具有广泛的种族分布。疾病最初表现为周围神经病及自主神经功能障碍,但随着病情的逐渐进展而导致越来越多的 Familial transthyretin amyloidosis is an inherited form of transthyretin-based amyloidosis characterized by autosomal dominant inheritance and has a broad Ethnic distribution. Disease initially manifested as peripheral neuropathy and autonomic dysfunction, but as the disease progresses and leads to more and more