目的总结重症急性胰腺炎(severe acute pancreatitis,SAP)的诊疗方法,分享其手术治疗经验。方法回顾性分析2007年1月到2012年1月我科收治的18例SAP患者临床资料,分析此病的临床特点、手术治疗方法和治疗效果。结果本组患者治愈12例,治愈率为66.7%;好转3例,好转率为16.7%;死亡2例,死因均为多器官衰竭,死亡率为11.1%,另有1例合并呼吸衰竭转入省级医院治疗。结论对SAP的手术治疗,应结合患者的实际情况来制定个体化治疗方案,同时掌握常用的手术方法,以做到尽可能提高患者的治愈率。 Objective To summarize the diagnosis and treatment of severe acute pancreatitis (SAP) and share the experience of surgical treatment. Methods The clinical data of 18 patients with SAP admitted in our department from January 2007 to January 2012 were retrospectively analyzed. The clinical features, surgical treatment and treatment effects were analyzed. Results The patients were cured in 12 cases, the cure rate was 66.7%; 3 cases improved, the improvement rate was 16.7%; 2 died, the cause of death were multiple organ failure, the mortality rate was 11.1%, and another case of respiratory failure combined Provincial hospital treatment. Conclusion The surgical treatment of SAP should be based on the actual situation of patients to develop individualized treatment programs, while master the common surgical methods, in order to achieve as much as possible to improve the cure rate of patients.