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慢性萎缩性胃炎(CAG)能否发生癌变是一个争论未决的问题。从胃癌高低发区CAG的调查结果来看,两者间可能存在着某种病因发病学的关系。本文的目的试图从CAG的超微病变来探讨其与胃癌发生间的关系。每例在胃镜下取材六块。16例活检组织经常规样品制备以日立H500型电镜观察;4例活检组织经二甲基亚砜液氮冷冻断裂法制样以日立S430型扫描电镜观察。并以正常人胃、小肠、大肠作对比观察。
The chronic problem of chronic atrophic gastritis (CAG) is cancerous. According to the findings of CAG in the high and low incidence areas of gastric cancer, there may be some etiological and pathological relationship between the two. The purpose of this paper is to explore the relationship between gastric cancer and the occurrence of gastric cancer from the ultrastructural lesions of CAG. Each case was obtained six pieces under gastroscopy. The biopsy specimens of 16 patients were observed by Hitachi Model H500 Electron Microscopy. Four samples of biopsies were sampled by liquid nitrogen freezing fracture method with Hitachi S430 scanning electron microscope. And normal human stomach, small intestine, large intestine for comparison observation.