金丝桃属植物Hypericum Drummondii中抗微生物和细胞毒活性的化合物

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金丝桃属植物在民间曾作为治疗肿瘤的药物。作者对密西西比沿岸植物进行考察时发现,H·Drummondii的根以及茎、叶的己烷提取物具有明显的抗微生物的活性。鉴于此属植物先前曾用于分离抗生素和抗真菌的Chromene,对上述提取物进行深入研究,从中分离出四种新化合物DrummondinsA、B、C和F以及两种Albaspidins A-A和P-P。 Hypericum used to treat cancer in the private sector. When examining plants on the Mississippian coast, the authors found that the hexane extract of H. Drummondii had significant antimicrobial activity at the roots and in stems and leaves. Given the genus Chromene that was previously used to isolate antibiotics and antifungal bacteria, the above extracts were further studied to isolate four new compounds, Drummondins A, B, C and F, and two Albaspidins A-A and P-P.
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