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目的动脉粥样硬化是一种炎性反应疾病,观察复方丹参滴丸对动脉粥样硬化炎症因子的影响。方法分为四组(对照组、AS组、复方丹参滴丸低剂量组和复方丹参滴丸高剂量组),分别测定血浆血脂指标及炎症因子指标(TNF-α、CRP及IL-1),所测数据进行T检验。结果 AS患者总胆固醇(TC)、甘油三脂(TG)和低密度胆固醇(LDL)均低于对照组,且随着复方丹参滴丸剂量增加,各个指标下降显著(P<0.05),高密度胆固醇(HDL)升高。复方丹参滴丸使炎症关键因子(TNF-α、CRP及IL-1)下降。结论复方丹参滴丸可以作为动脉粥样硬化控制药物
Objective Atherosclerosis is an inflammatory reaction disease, observe the impact of compound Danshen dripping pills on atherosclerotic inflammatory factors. Methods The rats were divided into four groups (control group, AS group, low dosage of compound Danshen dripping pills and high dosage of compound Danshen dripping pills). The levels of plasma lipids and inflammatory factors (TNF-α, CRP and IL-1) The measured data for T test. Results The total cholesterol (TC), triglyceride (TG) and low density cholesterol (LDL) in patients with AS were lower than those in the control group. The indexes of all the indexes decreased significantly (P <0.05) Cholesterol (HDL) is elevated. Compound Danshen dripping pills reduced the key factors of inflammation (TNF-α, CRP and IL-1). Conclusion Compound Danshen dripping pills can be used as atherosclerosis control drugs