论文部分内容阅读
目的:探究环磷酰胺联合激素治疗原发性肾病综合征的临床效果及安全性。方法:将本院收治的72例原发性肾病综合征患者按照入院治疗的先后顺序分为治疗组和对照组,其中治疗组采用环磷酰胺联合激素治疗;对照组则仅给予常规激素治疗,治疗结束后比较两组患者的临床治疗效果及不良反应情况。结果:治疗组患者的总缓解率为97.22%,对照组患者为77.78%,两组比较,差异具有统计学意义(P<0.05)。在治疗过程中,两组患者均无明显不良反应情况发生,临床用药安全可靠。结论:应用环磷酰胺联合激素对原发性肾病综合征进行治疗,临床效果显著,且不良反应较少。
Objective: To investigate the clinical effect and safety of cyclophosphamide combined with hormone in the treatment of primary nephrotic syndrome. Methods: 72 patients with primary nephrotic syndrome treated in our hospital were divided into treatment group and control group according to the sequence of admission treatment. The treatment group was treated with cyclophosphamide combined with hormone; the control group was given only conventional hormone therapy, After treatment, the clinical effects and adverse reactions of the two groups were compared. Results: The total remission rate was 97.22% in the treatment group and 77.78% in the control group. There was significant difference between the two groups (P <0.05). During the course of treatment, no obvious adverse reactions occurred in both groups, and the clinical medication was safe and reliable. Conclusion: The combination of cyclophosphamide and hormones in the treatment of primary nephrotic syndrome, the clinical effect was significant, and fewer adverse reactions.