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本研究对有骨代谢紊乱的中老年女性甲亢患者分组进行了传统西药及中西医结合治疗观察。治疗前，两组血Ｃａ（Ｃａ）及２４ｈ尿Ｃａ（Ｕ－Ｃａ）、尿Ｐ（Ｕ－ｐ）水平及血清降钙素水平均明显高于正常。患者血清Ｔ３与血Ｃａ水平呈正相关（ｒ＝０．６１４２，Ｐ＜０．０１），血Ｃａ与降钙素水平也呈正相关（ｒ＝０．５７１４，Ｐ＜０．０５）。治疗后，两组血Ｃａ及２４ｈＵ－Ｃａ、Ｕ－Ｐ及血清降钙素水平均有下降，但以中西医结合治疗的Ｂ组下降更明显。观察结果表明，对于中老年女性甲亢患者在用他巴唑等抗甲状腺药物治疗的同时采用补肾活血中药进行中西医结合治疗，可以有效地防止患者骨质丢失。
In this study, patients with hyperthyroidism in middle-aged and elderly women with bone metabolic disorders were treated with traditional western medicine and integrated traditional Chinese and Western medicine. Before treatment, blood calcium (Ca), 24-hour urinary Ca (U-Ca), urine P (U-p) levels, and serum calcitonin levels were significantly higher than normal. There was a positive correlation between serum T3 and serum Ca levels (r=0.6142, P<0.01), and a positive correlation between serum Ca and calcitonin levels (r=0.5714, P<0.05). After treatment, serum Ca, 24hU-Ca, U-P, and serum calcitonin levels decreased in the two groups, but the decline was more obvious in group B treated with Chinese and Western medicine. The observational results show that for middle-aged and elderly women with hyperthyroidism, the use of anti-thyroid drugs such as thiazole, and Bushen Huoxue Chinese medicine combined with traditional Chinese and western medicine treatment can effectively prevent bone loss in patients.