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作者在大鼠的失血性休克模型上观察了肝脏及血浆溶酶体酶的变化以及山莨菪碱对这些变化的影响,结果如下:一、将21只大鼠(体重150~250克)分成三组,①失血组(颈动脉放血至85mmHg维持2小时),②失血+654-2组(1mg/100g体重)。③手术对照组。最初及最大放血量在组①和组②间无明显差别,但失血后的代偿时间在组②较组①明显延长(分别为115.00±9.26与85.00±32.62分,P<0.05)
The authors observed changes in liver and plasma lysosomal enzymes and the effects of anisodamine on these changes in a rat model of hemorrhagic shock. The results were as follows: 1. Divide 21 rats (weighing 150-250 g) into three Group, ① blood loss group (carotid artery to 85mmHg for 2 hours), ② blood loss + 654-2 group (1mg / 100g body weight). ③ surgical control group. The initial and maximum blood loss did not differ between groups (1) and (2), but the compensatory time after hemorrhage was significantly prolonged in group② (115.00 ± 9.26 vs. 85.00 ± 32.62, P <0.05, respectively)