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分析胃贲门癌分泌粘液的性质,癌旁肠化上皮的类型,早期癌灶及不典型增生灶周围粘膜的性质,讨论贲门癌的组织发生。认为胃贲门癌起源于贲门粘膜腺颈部干细胞,不典型增生是贲门癌的癌前病变。溃疡、息肉在贲门癌发生上的重要性不大;贲门部萎缩性胃炎与肠上皮化生也只有当它具有明显的不典型增生性质时,才有癌变的可能;结肠型化生多数具有不典型增生性质,应予重视。
To analyze the nature of mucus secretion in gastric cardia cancer, the type of paracancerous intestinal epithelium, the characteristics of early lesions and surrounding mucosa of atypical hyperplasia, and discuss the histogenesis of cardiac cancer. It is believed that gastric cardia cancer originates from the cervical stem cells of the cardiac glands of the cardia, and dysplasia is a precancerous lesion of cardiac cancer. The importance of ulcers and polyps in the development of cardia cancer is not significant; atrophic gastritis and intestinal metaplasia of the cardia can only occur when it has obvious atypical hyperplasia, and colonic metaplasia mostly has The typical proliferative nature should be taken seriously.