论文部分内容阅读
目的:研究血清C-反应蛋白(CRP)与降钙素原(PCT)在儿童血液细菌感染诊断中的价值,为临床诊疗提供依据。方法:选取2012年1月到2016年1月我院收治的血液细菌感染患儿84例为研究组,另选取同期健康体检儿童106例为对照组。检测两组儿童血清CRP和PCT水平,并观察血清CRP和PCT的阳性预测值、阴性预测值、灵敏度和特异度。结果:研究组血清CRP、PCT水平和阳性率均显著高于对照组,比较差异具有统计学意义(P<0.05);血清PCT诊断的特异度、灵敏度、阴性预测值和阳性预测值分别为84.91%、92.86%、93.75%、82.98%,均分别显著高于血清CRP的67.92%、50.00%、63.16%、55.26%,比较差异均具有统计学意义(P<0.05)。结论:血清CRP和PCT对儿童血液细菌感染均具有一定诊断价值,但是血清PCT的诊断效能更高。
Objective: To investigate the value of serum C-reactive protein (CRP) and procalcitonin (PCT) in the diagnosis of bacterial infection of blood in children and provide the basis for clinical diagnosis and treatment. Methods: From January 2012 to January 2016, 84 children with bacterial infection of blood in our hospital were selected as the study group, and 106 healthy children in the same period were selected as the control group. Serum levels of CRP and PCT were detected in both groups. The positive predictive value, negative predictive value, sensitivity and specificity of serum CRP and PCT were also observed. Results: The levels of serum CRP, PCT and the positive rate in the study group were significantly higher than those in the control group (P <0.05). The specificity, sensitivity, negative predictive value and positive predictive value of serum PCT diagnosis were 84.91 %, 92.86%, 93.75% and 82.98%, respectively, were significantly higher than those of serum CRP 67.92%, 50.00%, 63.16% and 55.26% respectively, with statistical significance (P <0.05). Conclusion: Both serum CRP and PCT have certain diagnostic value in children with bacterial infection of blood, but the diagnostic efficiency of serum PCT is higher.