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目的：观察注射用海王降纤酶治疗急性脑梗死的有效性和安全性。方法：对发病24h内的60例急性脑梗死患者应用海王降纤酶进行降纤治疗，使用海王降纤酶10U加生理盐水100ml静脉点滴，第3，5天各用海王降纤酶5U加生理盐水100ml静脉点滴。结果:使用海王降纤酶越早的病人，偏瘫偏麻、失语治疗效果越好，显效率达到88．33%。与对照组（66．67%）相比，有显著性差异。结论：海王降纤酶治疗急性脑梗死效果好，可以在临床上推广使用。
Objective: To observe the efficacy and safety of Haiwang defibrase in the treatment of acute cerebral infarction. Methods: 60 cases of acute cerebral infarction within 24 hours of onset of application of Neptuno defibrase for fibrinolytic therapy, the use of sea king defibrase 10U intravenous drip with saline 100ml, the first 3,5 days with Nepali defibrase 5U plus physiology 100ml saline intravenous drip. Results: The earlier the patients using Neptune defibrase, partial hemiplegia Ma, the better treatment of aphasia, markedly effective rate of 88.33%. Compared with the control group (66.67%), there was a significant difference. Conclusion: Haiwang defibrase is effective in treating acute cerebral infarction and can be widely used clinically.