长效口服避孕药的主要优点是一月服一次,比较简便,避孕效果可靠,成功率在98％左右。但目前还存在着一些问题,如副反应较高,特别是开始服药时的类早孕反应(包括恶心、呕吐、头晕、头痛、嗜睡等发生率约为50％),服药三个月后白带增多(发生率以后维持在50％左右),使一些服药者不能克服而停药。会议提出今后有待在克服副反应方面狠下功夫。根据临床观察,考虑其主要副反应如类早孕反应及白带增多均由于雌激素过多引起,减少雌激素的含量来降低副反应是值得探讨的一个重要方面,上海代表报告曾试在服全量复方氯地孕酮一定时期后改服减量片,实验室观察 Long-term oral contraceptives main advantage is that once a month, more convenient, reliable contraception, the success rate of about 98%. However, there are still some problems, such as high side effects, especially early pregnancy reaction (including nausea, vomiting, dizziness, headache, drowsiness and other incidence of about 50%) when taking medication, leucorrhea increased three months after taking the drug (The incidence remained at about 50%), so that some drug users can not overcome the withdrawal. The meeting proposed that hard work should be done in overcoming side effects in the future. According to clinical observation, taking into account the main side effects such as early pregnancy reaction and leucorrhea increased due to excessive estrogen, reducing estrogen levels to reduce side effects is an important aspect worth exploring, the Shanghai representative reported that the full trial of compound Chlormadinone after a certain period of service to reduce the amount of tablets, laboratory observations