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目的探讨甲状腺结节内钙化在诊断甲状腺癌中的意义。方法回顾性分析306例结节性甲状腺肿伴钙化患者的术前彩色多普勒超声检查及术后病理结果。结果经病理确诊为甲状腺癌157例占306例结节性甲状腺肿伴钙化患者的比例为51.31%(157/306),其中乳头状癌126例所占比例为80.25%,滤泡状癌13例为8.28%,未分化癌10例为6.37%,髓样癌8例为5.10%。微小钙化在306例钙化中比例为65.5%(200/306),其中乳头状癌为73.81%(93/126);微小钙化比例在不同年龄组之间(≥45岁和<45岁)分别为39.33%、67.95%,二者间存在显著差异(P<0.05)。结论超声可早期发现甲状腺钙化,对诊断甲状腺癌临床诊断价值大。
Objective To investigate the significance of thyroid nodules calcification in the diagnosis of thyroid cancer. Methods A retrospective analysis of 306 cases of nodular goiter with calcification in patients with preoperative color Doppler ultrasound and postoperative pathological results. Results The pathological diagnosis of 157 cases of thyroid cancer accounted for 306 cases of nodular goiter with calcification in 51.31% (157/306), of which 126 cases of papillary carcinoma was 80.25%, follicular carcinoma in 13 cases 8.28%, undifferentiated carcinoma in 10 cases was 6.37%, medullary carcinoma in 8 cases was 5.10%. The proportion of microcalcification in the 306 cases of calcification was 65.5% (200/306), of which the papillary carcinoma was 73.81% (93/126). The proportion of microcalcifications in different age groups (≥45 years and <45 years) were 39.33%, 67.95%, there was a significant difference between the two (P <0.05). Conclusion Ultrasound can be found early thyroid calcification, the clinical diagnosis of thyroid cancer diagnosis.