论文部分内容阅读
目的:观察腹膜透析对终末期糖尿病肾病患者高敏C反应蛋白(high sensitivity C-reactive protein,hs-CRP)及晚期氧化蛋白产物(advanced oxidation protein products,AOPP)的影响。方法:检测终末期糖尿病肾病非透析患者36例(A组)、持续性非卧位腹膜透析(continuous ambulatory peritoneal dialysis,CAPD)时间≤1 a患者40例(B组)、CAPD时间>1 a患者36例(C组)血清hs-CRP及AOPP水平,并进行比较。结果:B,C组血清hs-CRP水平高于A组(P<0.01);C组血清hs-CRP水平高于B组(P<0.01);C组血清AOPP水平高于A,B组(P<0.01),A组血清AOPP水平高于B组(P<0.01)。结论:CAPD治疗<1 a终末期糖尿病患者血清AOPP水平降低,此后呈增高趋势,hs-CRP水平呈持续增高趋势。
Objective: To observe the effect of peritoneal dialysis on high sensitivity C-reactive protein (hs-CRP) and advanced oxidation protein products (AOPP) in patients with end stage diabetic nephropathy. Methods: Thirty-six patients with end-stage diabetic nephropathy (group A), 40 patients (group B) with continuous ambulatory peritoneal dialysis (CAPD) ≤1 a, patients with CAPD> 1 year 36 cases (group C) serum hs-CRP and AOPP levels, and compared. Results: The serum hs-CRP levels in group B and group C were higher than those in group A (P <0.01). The serum hs-CRP levels in group C were higher than those in group B (P <0.01) P <0.01). The serum AOPP level in group A was higher than that in group B (P <0.01). Conclusion: The serum AOPP level of patients with end-stage diabetes mellitus with CAPD <1 a decreased, then increased, and hs-CRP level continued to increase.