论文部分内容阅读
目的 探讨肝硬化病人空腹血浆胃动素水平的变化及其与肝功能损害的关系。方法 应用放免法检测肝炎肝硬化病人、慢性肝炎病人和正常人空腹血浆胃动素，并进行比较。结果 肝硬化病人平均空腹血浆胃动素水平的变化及异常率（＞ ３１２ ｎｇ／ｍ ｌ为异常）均明显高于慢性肝炎和正常人，且Ｃｈｉｌｄ Ｃ级＞ Ｂ级＞ Ａ级。肝硬化时空腹血浆胃动素水平与血浆白蛋白呈负相关，与血清总胆红素呈正相关。结论 肝硬化病人空腹血浆胃动素水平明显升高，与肝功能损害程度有关。
Objective To investigate the changes of fasting plasma motilin in patients with liver cirrhosis and its relationship with liver dysfunction. Methods Fasting plasma motilin was detected by radioimmunoassay in patients with cirrhosis, chronic hepatitis and normal subjects. Results The average fasting plasma motilin level and abnormal rate (> 312 ng / ml) in cirrhotic patients were significantly higher than those in chronic hepatitis and normal controls, and Child C> B> A. Fasting plasma motilin levels in cirrhotic patients were negatively correlated with plasma albumin and positively correlated with serum total bilirubin. Conclusion The level of fasting plasma motilin in patients with cirrhosis is significantly increased, which is related to the degree of liver dysfunction.