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本文作者报道了三例睾丸酮替代治疗过程中出现的前列腺并发症。例1.因慢性阻塞性肺病合并广泛性骨质疏松及胸椎楔形变形和性功能减退,用环戊丙酸睾丸酮治疗,200mg肌注/3周。用药前前列腺扪诊正常,10周后出现尿流变细,前列腺门及硬结节,前列腺特异抗原(PSA)增高,活检证实为前列腺腺癌。例2.因骨质疏松,髋关节骨折及性功能减退,用环戊丙酸睾丸酮200mg肌注/3周,19个月后出现两叶前列腺变硬,PSA增高,活检诊断为前列腺腺癌。例3.因右侧睾丸切除,
The authors reported on the complication of prostate in three cases of testosterone replacement therapy. Example 1. Chronic obstructive pulmonary disease with extensive osteoporosis and thoracic wedge deformation and sexual dysfunction, with cypionate testosterone treatment, 200mg intramuscular injection / 3 weeks. Prostate palpation normal before treatment, 10 weeks after the emergence of thin urinary tract, prostate and hard nodules, prostate-specific antigen (PSA) increased biopsy confirmed as prostate cancer. Example 2 due to osteoporosis, hip fracture and sexual dysfunction, intramuscular injection of 200mg testosterone cypionate / 3 weeks, 19 months after the emergence of two leaves of the prostate stiffen, PSA increased biopsy diagnosed as prostate cancer. Example 3 due to the right testicle excision,