胰岛素抵抗与胰岛素分泌缺陷是2型糖尿病的主要病理生理学缺陷。绝大多数的欧美2型糖尿病患者均肥胖,而肥胖所致的胰岛素抵抗被认为是导致该人群发生2型糖尿病的最主要因素。但是亚洲2型糖尿病患者中,肥胖者还不到半数。胰岛素抵抗抑或胰岛素分泌功能缺陷是亚洲糖尿病患者早期发病的主要因素尚不明了。本文调查了解中国新诊断的2型 Insulin resistance and insulin secretion defects are the major pathophysiological deficits in type 2 diabetes. The vast majority of patients with type 2 diabetes in Europe and the United States are obese, and obesity-induced insulin resistance is considered to be the leading cause of type 2 diabetes in this population. But in Asian patients with type 2 diabetes, obese less than half. Insulin resistance or insulin secretion deficiency is the main factor in the early onset of diabetes in Asia is not yet clear. This article investigates the newly diagnosed type 2 in China