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目的BTA检测与尿脱落细胞学检查结果比较,以明确在膀胶癌诊断中的应用价值.方法 收集1996年12月～1997年1月经膀胱镜及病理学检查确诊为膀胱乳头状移行细胞癌的病人共47例.每一例于膀胱镜检查前连续留取三次晨尿,行尿脱落细胞学检查.最后一次标本同时行BTA检测及尿液常规化验.结果BTA检测膀胱癌的敏感度为70.2%(33/47),尿脱落细胞学检查敏感度为25.5%(12/47),两者有非常显著性差异(P<0.001).共有8例(17.0%)患者两种检查结果均为阳性,10例(21.3%)患者两种检测结果均为阴性.另外,BTA检测对T1期膀胱癌患者的敏感度明显高于尿脱落细胞学检查,其结果分别为76.0%(19/25)和12.0%(3/25),统计学分析示有非常显著性差异(P<0.01).结论 BTA检测是一种有价值的膀胱癌诊断辅助措施,且使用方便,检测迅速,无创伤性,便于临床开展.
Objective BTA test and urine cytology results compared to clear in the diagnosis of bladder cancer value.Methods From December 1996 to January 1997 by cystoscopy and pathology confirmed the diagnosis of bladder papillary transitional cell carcinoma A total of 47 patients in each case in the cystoscopy before taking three times morning urine urine cytology.At the same time the final specimen BTA and urine routine tests.Results BTA detection of bladder cancer sensitivity was 70.2% (33/47). The sensitivity of exfoliative cytology was 25.5% (12/47), with significant difference (P <0.001) .A total of 8 patients (17.0%) had positive results of both tests , And 10 cases (21.3%) were negative in both tests.In addition, the sensitivity of BTA to T1 bladder cancer was significantly higher than that of urine cytology (76.0%, 19/25) and (P <0.01) .Conclusion BTA is a valuable auxiliary diagnosis of bladder cancer, and it is easy to use, rapid and non-invasive Clinical development.