通过对８例慢性阻塞性肺疾病（ＣＯＰＤ）继发急性呼吸衰竭患者机械通气及撤机的临床实践，探讨了ＣＯＰＤ病人机械通气的治疗及其撤机的方法和技术，以及撒机成功所需达到的呼吸生理指标，认为ＣＯＰＤ病人撤机中最重要的是确保试脱机前ＰａＣＯ２等呼吸生理指标接近病人缓解期水平。 Through the clinical practice of mechanical ventilation and weaning in 8 patients with chronic obstructive pulmonary disease (COPD) secondary to acute respiratory failure, the methods and techniques of mechanical ventilation and weaning of COPD patients were discussed, Reached respiratory physiology, that the weakest COPD patients weaning the most important is to ensure that before taking off the test PaCO2 and other respiratory physiological indicators close to the level of patient remission.