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目的探讨甲硝唑缓释药膜治疗牙周炎患者的临床疗效。方法选取2013年2月至2016年2月于辽阳市第八人民医院就诊的90例牙周炎患者作为研究对象,按随机数字表法将其分为观察组(50例)和对照组(40例)。对照组患者给予碘甘油,观察组患者采用甲硝唑缓释药膜进行治疗,比较两组患者临床效果、不良反应发生情况及治疗前后牙龈出血量、牙龈指数、牙周袋深度。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的牙龈出血量明显少于对照组,牙龈指数、牙周袋深度均明显小于对照组,差异均有统计学意义(均P<0.05)。结论应用甲硝唑缓释药膜治疗牙周炎,可以有效改善患者症状,以及牙龈指数与牙周袋深度,提高临床疗效,安全性较高。
Objective To investigate the clinical effect of metronidazole sustained-release film in patients with periodontitis. Methods Totally 90 patients with periodontitis treated in Liaoyang No.8 People’s Hospital from February 2013 to February 2016 were selected as study subjects and divided into observation group (50 cases) and control group (40 cases) by random number table method example). Patients in the control group were treated with iodine and glycerol. Patients in the observation group were treated with sustained-release metronidazole membrane. The clinical effects, incidence of adverse reactions, gingival bleeding, gingival index and periodontal pocket depth before and after treatment were compared between the two groups. Results The total effective rate of observation group was significantly higher than that of control group (P <0.05). After treatment, the bleeding volume of observation group was less than that of control group, and the gingival index, periodontal pocket depth Obviously smaller than the control group, the difference was statistically significant (all P <0.05). Conclusion The application of metronidazole sustained-release film in the treatment of periodontitis can effectively improve the symptoms, the gingival index and the depth of the periodontal pocket, and improve the clinical efficacy and safety.