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免疫机能低下或免疫缺陷者于病毒感染时症状加重。疱疹病毒属的感染从潜伏状态再发,常引起致死性的全身感染症。目前使用的抗病毒药主要针对疱疹属病毒和人类免疫缺陷病毒感染症。单纯疱疹病毒及水痘—带状疱疹病毒感染症使用无环岛苷(ACV)、阿糖腺苷(ara—A)、疱疹净(IDU)等。巨细胞病毒及单纯疱疹病毒感染症使用DHPG。人类免疫缺陷病毒感染症在日本使用叠氮胸苷。
Immune dysfunction or immunodeficiency in patients with symptoms of infection increased. Herpes virus infection from the latent recurrence, often causing fatal systemic infection. Currently used antiviral drugs are mainly targeted herpes virus and human immunodeficiency virus infection. Herpes simplex virus and varicella-zoster virus infection use acylinosine (ara-A), herpes simplex (IDU) and so on. Cytomegalovirus and herpes simplex virus infection using DHPG. Human immunodeficiency virus infection uses zidovudine in Japan.