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通常认为发病于儿童和青春期的慢性胰腺炎临床少见,多表现为家族性胰腺炎。但作者发现不少慢性胰腺病人的最初症状出现于儿童和青春期。故分析了69例确诊为慢性胰腺炎的临床资料,将胰腺炎首发症状出现在20岁以前的病历调出。所有患者均具一项以上如下诊断标准:1)有反复发作或持续性胰腺炎的腹痛病史。2)有一次以上的血清淀粉酶升高。3)有腹平片或 CT 及 ERCP 可见的胰腺钙化。并详细分析与其有关的全部资料,研究截止于1991年3月。结果表明,已确诊的69例慢性胰腺炎中10例最初症状出现于20岁以前,其中6例为女性。发病时平均年龄13.5岁(3~17岁),以59例成年发病患者中13例为对照组,后者为39岁(21~69岁)。本组中3例有家族史,7例有饮酒史,最小者13岁开始饮酒。3例发病期依赖麻醉剂。10例中6例胰管扩张达10mm
Chronic pancreatitis is generally considered clinically uncommon in children and adolescence, and is mostly characterized by familial pancreatitis. But the authors found that many of the first symptoms of chronic pancreatic patients appear in children and adolescence. Therefore, the analysis of 69 cases of chronic pancreatitis was diagnosed as clinical data, the first symptom of pancreatitis appeared in the medical records before the age of 20 recall. All patients with more than one of the following diagnostic criteria: 1) recurrent or persistent pancreatitis history of abdominal pain. 2) more than one serum amylase increased. 3) There are abdominal plain film or CT and ERCP visible pancreatic calcification. And a detailed analysis of all the relevant information, the study ended in March 1991. The results showed that the initial diagnosis of 69 cases of chronic pancreatitis occurred in 10 cases before the age of 20, of which 6 were female. The mean age at onset was 13.5 years (range, 3 to 17 years), with 13 of 59 adult-onset patients as control and the latter 39 years (21-69 years). In this group, 3 cases had a family history, 7 cases had a history of drinking, the youngest 13-year-old started drinking. 3 cases dependent on anesthesia during the onset. 6 cases of 10 cases of pancreatic duct expansion of up to 10mm