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卒中是中国第一位致残和第二位致死原因。血脂异常是缺血性卒中/短暂脑缺血发作的重要危险因素之一,其中低密度脂蛋白胆固醇(LDL-C)的升高使得缺血性卒中风险增加。他汀类药物(3羟基3甲基戊二酰辅酶 A 还原酶抑制剂)是治疗高胆固醇血症和防治动脉粥样硬化性疾病最重要的药物。目前对他汀类药物防治卒中的认识尚不一致。因此,有必要尽快统一认识,规范他汀类药物的治疗策略。中华内科杂志特邀请国内有关专家对此进行了充分的讨论,达成他汀类药物防治脑血管病专家建议,以期给临床医生以明确的临床指导。
Stroke was the first cause of disability and the second leading cause of death in China. Dyslipidemia is one of the major risk factors for ischemic stroke / transient ischemic attack, in which elevated LDL-C leads to an increased risk of ischemic stroke. Statins, the 3-hydroxymethyl-3-methylglutaryl coenzyme A reductase inhibitor, are the most important drugs for treating hypercholesterolemia and preventing and treating atherosclerotic disease. At present, the understanding of statin prevention and treatment of stroke is not the same. Therefore, it is necessary to unify understanding and regulate the treatment strategy of statins as soon as possible. Chinese Internal Medicine magazine invited domestic experts to conduct a full discussion, reached statin prevention and treatment of cerebrovascular disease expert advice, with a view to clinicians with a clear clinical guidance.